DISTINCT RESTING-STATE EFFECTIVE CONNECTIVITY OF LARGE-SCALE NETWORKS IN FIRST-EPISODE AND RECURRENT MAJOR DEPRESSION DISORDER: EVIDENCE FROM THE REST-META-MDD CONSORTIUM

IntroductionPrevious studies have shown disrupted effective connectivity in the large-scale brain networks of individuals with major depressive disorder (MDD).However, it is unclear whether these changes differ between first-episode drug-naive MDD (FEDN-MDD) and recurrent MDD (R-MDD).MethodsThis study utilized resting-state fMRI data from 17 sites

In the last few years a new line of research has appeared in the literature.This line ofresearch, which may be referred to as experimental semiotics (Galantucci, 2009; Galantucci& Garrod, 2010), focuses on the crb concept experimental investigation of novel forms of humancommunication.In this review we biab spirited will (a) situate experimenta

Henry Devlin,1,* Stephanie Fulaz,1,* Dishon Wayne Hiebner,1 James P O’Gara,2 Eoin Casey1 1UCD School of Chemical and Bioprocess Engineering, University College Dublin, Dublin, Ireland; 2Department of Microbiology, School of Natural Sciences, National University of Ireland, Galway, Ireland*These authors contributed equally to this workCorrespo

Background and Objectives: A recent clinical trial has demonstrated that breast cancer with low-HER2 expression levels responds to trastuzumab deruxtecan treatment.This has prompted sensationnel brielle a re-evaluation of HER2-targeted therapies in the HER2-negative group.Further research is required in the form of more detailed information about H

Vitamin D signaling modulates a variety of immune responses.Here, sensationnel brielle we assessed the role of vitamin D in immunity to experimental leishmaniasis infection in vitamin D receptor-deficient mice (VDRKO).We observed that VDRKO mice on a genetically resistant background have decreased Leishmania major-induced lesion development compare